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Alsene, 2003
Alsene K. et al. (2003) Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology, 28(9): 1694-702.
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APA, 2013
American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM V) ISBN 978-0-89042-554-1DSMV.
Hits: 374
Arendash, 2006
Arendash G.W. et al. (2006) Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. Neuroscience, 142(4): 941-52.
Hits: 282
Armstrong, 2007
Armstrong L.E. et al. (2007) Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance. Exerc Sport Sci Rev, 35(3): 135-40.
Hits: 321
Boekema, 2001
Boekema P.J. et al. (2001) Functional bowel symptoms in a general Dutch population and associations with common stimulants. Netherlands J Med, 59(1): 23-30.
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Booth, 1992
Booth D.A. et al. (1992) Personal benefits from post-ingestional actions of dietary constituents. Proc Nutr Soc, 51: 335–341.
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Branum, 2014
Branum A.M. et al. (2014) Trends in caffeine intake among U.S. children and adolescents, Pediatrics, 133(3):386-393
Hits: 314
Breda, 2014
Breda J.J et al. (2014) Energy drink consumption in Europe: a review of the risks, adverse health effects, and policy options to respond. Frontiers in Public Health, 2:1-5
Hits: 294
Byrne, 2012
Byrne E.M. et al. (2012) A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor. Sleep, 35(7): 967-75.
Hits: 310
Caldeira, 2013
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Cao, 2009
Cao C. et al. (2009) Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice. J Alzheimers Dis, 17(3): 681-97.
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CARE Study group, 2008
CARE Study Group (2008) Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. Br Med J, 337:a2332.
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Chen, 2003
Chen J.F. (2003) The adenosine A(2A) receptor as an attractive target for Parkinson's disease treatment. Drug News Perspect, 16(9): 597-604.
Hits: 310
Cornelis, 2007a
Cornelis M. et al. (2007) Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption. Am J Clin Nutr, 86: 240-244.
Hits: 305
Costa, 2010
Costa J. et al. (2010) Caffeine exposure and the risk of Parkinson's disease: a systematic review and meta-analysis of observational studies. J Alzheimers Dis, 20 Suppl 1: S221-38.
Hits: 301
Du, 2005
Du Y. et al. (2005) Association of serum caffeine concentrations with blood lipids in caffeine-drug users and nonusers - results of German National Health Surveys from 1984 to 1999. Eur J Epidemiol, 20(4):311-6.
Hits: 299
EFSA, 2011a
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) (2011) Scientific Opinion on the substantiation of health claims related to caffeine and increased fat oxidation leading to a reduction in body fat mass (ID 735, 1484), increased energy expenditure leading to a reduction in body weight (ID 1487), increased alertness (ID 736, 1101, 1187, 1485, 1491, 2063, 2103) and increased attention (ID 736, 1485, 1491, 2375) pursuant to Article 13(1) of Regulation (EC) No 1924/20061. EFSA Journal; 9(4): 2054.
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EFSA, 2011b
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) (2011) Scientific Opinion on the substantiation of health claims related to caffeine and increase in physical performance during short-term high-intensity exercise (ID 737, 1486, 1489), increase in endurance performance (ID 737, 1486), increase in endurance capacity (ID 1488) and reduction in the rated perceived exertion/effort during exercise (ID 1488, 1490) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal; 9(4): 2053 [24 pp.]. doi:10.2903/j.efsa.2011.2053
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EFSA, 2011c
EFSA (2011) 'The EFSA Comprehensive European Food Consumption Database' Available at:
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Ellison, 1995
Ellison R.C. et al. (1995) Current caffeine intake of young children: amount and sources. J Am Diet Assoc, 95(7): 802-4.
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Fredholm, 1999
Fredholm B.B. et al. (1999) Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev, 51:83-133.
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French, 1994
French J.A. et al. (1994) Caffeine and mood: individual differences in low-dose caffeine sensitivity. Appetite, 22: 277–279.
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Geleijnse, 2008
Geleijnse J.M. (2008) Habitual coffee consumption and blood pressure: an epidemiological perspective. Vasc Health Risk Manag, 4(5): 963-70.
Hits: 307
Hallström, 2013b
Hallström H. et al. (2013) Long-term coffee consumption in relation to fracture risk and bone mineral density in women. Am J Epidemiol, 178(6): 898-909.
Hits: 306
Harland, 2000
Harland B.F. (2000) Caffeine and nutrition. Nutrition, 7/8: 522-526.
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Health Canada, 2013
Health Canada. (2013) Health Canada Reminds Canadians to Manage Their Caffeine Consumption
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Heaney, 2002
Heaney R.P. (2002) Effects of caffeine on bone and the calcium economy. Food Chem Toxicol, 40: 1263-70.
Hits: 324
Heckman, 2010
Heckman M.A. et al. (2010) Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. J Food Sci, 75: R77-87.
Hits: 321
Illy, 1995
Illy A. et al. (1995) Espresso Coffee. The chemistry of quality. Academic Press, London.
Hits: 295
Jee, 2001
Jee S.H. et al. (2001) Coffee consumption and serum lipids: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol, 153(4):353-62.
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Kim, 2013a
Kim J. et al. (2013) Association between coffee intake and gastroesophageal reflux disease: a meta-analysis. Dis Esophagus. 2013 Jun 24.doi: 10.1111/dote.12099. [Epub ahead of print].
Hits: 303
Liu, 2012
Liu H. et al. (2012) Coffee consumption and risk of fractures: a meta-analysis. Arch Med Sci, 8(5):776-83.
Hits: 303
March of Dimes, 2012
March of Dimes (2012) Caffiene in Pregnancy
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Meltzer, 2008
Meltzer H M. et al. (2008) Risk assessment of caffeine among children and adolescents in the Nordic countries, Nordic Council of Ministers
Hits: 298
Mitchell, 2013
Mitchell D.C. et al. 2013, Beverage caffeine intakes in the U.S. Food Chem Toxicol, 2013 Nov 1. [Epub ahead of print]
Hits: 310
Mitchell, 2014
Mitchell D.C. et al. (2014) Beverage caffeine intakes in the U.S. Food & Chemical Toxicology, 63:136-142
Hits: 308
Moayyedi, 2000
Moayyedi P. et al. (2000) The Proportion of Upper Gastrointestinal Symptoms in the Community Associated with Helicobacter pylori: Lifestyle Factors, and Non-Steroidal Anti-inflammatory drugs. Am J Gastroenterol, 95 (6): 1448-1455.
Hits: 307
Mostofsky, 2012
Mostofsky E. et al. (2012) Habitual coffee consumption and risk of heart failure: a dose-response meta-analysis. Circ Heart Fail, 5(4): 401-5.
Hits: 352
Nehlig, 1999
Nehlig A. (1999) Are we dependent upon coffee and caffeine? A review on human and animal data. Neurosci Biobehav Rev, 23(4): 563-76.
Hits: 319
Noordzij, 2005
Noordzij M. et al. (2005) Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens, 23(5): 921-8.35.
Hits: 300
Palatini, 2009
Palatini P. et al. (2009) CYP1A2 genotype modifies the association between coffee intake and the risk of hypertension. J Hypertens, 27(8): 1594-601.
Hits: 294
Pelchovitz, 2011
Pelchovitz D.J. et al. (2011) Caffeine and cardiac arrhythmias: a review of the evidence. Am J Med, 124(4): 284-9.
Hits: 308
Porkka-Heiskanen, 2011
Porkka-Heiskanen T. (2011) Methylxanthines and sleep. Handb Exp Pharmacol, 200: 331-48.
Hits: 349
Rauh, 2006
Rauh R. et al. (2006) Acute effects of caffeine on heart rate variability in habitual caffeine consumers. Clin Physiol Funct Imaging, 26(3): 163-6.
Hits: 314
Rétey, 2007
Rétey J.V. et al. (2007) A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep. Clin Pharmacol Ther, 81: 692-8.
Hits: 321
Rogers, 2010
Rogers P.J. et al. (2010) Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption. Neuropsychopharmacology, 35(9): 1973-83.
Hits: 292
Rubach, 2011
Rubach M. et al. (2011) Multi-parametric approach to identify coffee components that regulate mechanisms of gastric acid secretion. Mol Nutr Food Res, 56(2): 325-35.
Hits: 286
Rudolph, 2014
Rudolph E. et al. (2014) Caffeine intake from all sources in adolescents and young adults in Austria, European Journal of Clinical Nutrition, 68(7):793-8
Hits: 285
Ruxton, 2008

Ruxton C.H.S. (2008) The impact of caffeine on mood, cognitive function, performance and hydration: a review of benefits and risks. Nutr Bull, 33: 15–25.

Hits: 292
Ruxton, 2014
Ruxton C.H.S. (2014) The suitability of caffeinated drinks for children: a systematic review of randomised controlled trials, observational studies and expert panel guidelines, Journal of Human Nutrition & Dietetics, 27:342-357
Hits: 291
Sachse, 1999
Sachse C. et al. (1999) Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol, 47(4): 445-9.
Hits: 292
SCF, 1983
Scientific Committee for Food (1983) Report of the Scientific Committee for Food on Caffeine.
Hits: 335
Shimamoto, 2013
Shimamoto T. et al. (2013) No Association of Coffee Consumption with Gastric Ulcer, Duodenal Ulcer, Reflux Esophagitis, and Non-Erosive Reflux Disease: A Cross-sectional study of 8,013 Healthy Subjects in Japan. PLoS One, 8(6); e65996.
Hits: 313
Verhoef, 2002
Verhoef P. et al. (2002) Contribution of caffeine to the homocysteine-raising effect of coffee: a randomized controlled trial in humans. Am J Clin Nutr, 76(6): 1244-8.
Hits: 320
Wu, 2009
Wu J.N. et al. (2009) Coffee consumption and risk of coronary heart diseases: a meta-analysis of 21 prospective cohort studies. Int J Cardiol, 137(3): 216-25.
Hits: 329